Genetics

Original Gene Sequence: 3'-T AC CC T. TT AGTAGCCAC T-5

Transcription of Original: 3'-A UG GG A AA UCAUCGGUG A-5'

Translation of Original: Start codon Met, Gly, Asn, His, Arg, Stop

Mutated Gene Sequence 1: 3'-T ACGCT TT AGTAGCCAT T-5'

Transcription of Mutated 1: 3'-A UGCGA AA UCAUCGGUA A-5'

Translation of Mutated 1: Start codon Met, Arg, Asn, His, Arg, Stop

Mutated Gene Sequence 2: 3'-T AACCT TT ACTAGGCAC T-5'

Transcription of Mutated 2: 3'-AUUGGAAAUGAUCCGUGA

Translation of Mutated 2: Ile, Gly, Asn, Asp, Pro, Stop

The first and last codons of the sequences are the start and stop codons respectively. The start codon indicates where transcription should begin. The stop codon indicates where transcription should end.

When a mutation occurs in the start codon, transcription will not be initiated and thus a protein will not be produced. When a mutation in the stop codon occurs sometimes the mutation will...
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