Pathophysiology of Diabetes Mellitus II

The patient is a male 45 years of age who has been diagnosed with Metabolic Syndrome many years ago but most recently has been diagnosed with Type 2 Diabetes Mellitus. The patient presents expressing concerns that he may have had high blood sugars prior to the recent diagnosis. It is necessary to explain to the patient that Type 2 Diabetes Mellitus is comprised by a range of dysfunctions "characterized by hyperglycemia and resulting from the combination of resistance to insulin action, inadequate insulin secretion and excessive or inappropriate glucagon secretion." (Khardoni, 2014, p. 1)

Type 2 Diabetes Mellitus is reported to be a "heterogeneous disorder with varying prevalence among different ethnic groups." (Death to Diabetes, 2014, p. 1) The primary events of DM are held to be "an initial insensitivity of insulin resulting in peripheral insulin resistance; and later on, relative insulin deficiency." (Death to...
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