Systemic Lupus Erythematosus Case Study

Systemic Lupus Erythematosus

Systemic lupus erythematosus (SLE) is a chronic, life-long autoimmune disease that affects multiple tissues and organs in the body (Madhok and Wu, 2009). The primary tissues and organs affected by immune system dysfunction are the joints, kidneys, vessel walls, and skin. SLE is believed to be due to an interaction between genetic factors and environmental triggers. The disease is also more prevalent among women, which is consistent with the possibility that hormones play some role in disease etiology.

Of primary concern is lupus glomerulonephritis (Madhok and Wu, 2009). Other serious complications include cardiovascular and neuropsychiatric involvement. Most patients will experience arthritis or joint pain (84%), fever (52%), malar rash (58%), and photosensitivity (45%). Accordingly, a diagnosis of SLE will depend in part on a blood test for anti-nuclear antibodies (ANA) and presentation with rash, joint pain, fatigue, and/or low-grade fevers.

The pain...
[ View Full Essay]