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Essay Instructions: what are the possible problems with gene therapy? Consider the capitalist angle of anything to make a buck. consider the issue of who gets access to genetic modification. Consider our history of natural selection. From a race/class perspective draw parallels between treatment of (movies Brave new world/Gattaca and people today or how people may act in the future...give pros and cons of gene therapy

Essay Instructions: Paper is for Genetics.
I have chosen the topic.
Genetic Pathway of breast cancer and gene therapy as it relates to breast cancer.

Essay Instructions: ALL PDF FILES NEEDED HAVE BEEN UPLOADED.

TOPIC - “critically analyse how scientific developments within cancer care impact upon clinical practice”

The medical focus of the interventions/treatment on Lung Cancer and the physical/psychological impact upon the individual and related care issue.

Address lung cancer explaining how gene therapy is helping, and how radiotherapy has developed along with how this impacts on clinical nurse practices.

Areas that might be included in paper: Cell growth Control and Cancer and Molecules, Genes and cancer

This paper should also contain a critical review of relevant literature.

All scientific aspects that are discussed are balanced with pertinent issues from professional practice.

Note:
This paper is to be written from the point of view of a Cancer NURSE specialist.

There are faxes for this order.

Essay Instructions: A 4Page Paper focussing on the recent advances in understanding the genetic underpinnings of one of the five following diseases: alcoholism; using Research Material Provided in the Books and Websites (mandatory)

Use of quotations to support or state claims allowed but must be clearly shown. (Answer Questions a-h in your essay).

Books and Webisites(sources)

1. Freeman, Scott. ?Genomes?. Chapter 16,
2. The Gene Masters: How A New Breed of Scientific Entrepreneurs Raced For the Biggest Prize In Biology. New York: Henry Holt (Times Books), 2002. 5-17, 41-57, 82-92, and 154-59

Websites:-

http://www.ncbi.nlm.nih.gov/disease/

http://www.ncbi.nlm.nih.gov/omim

http://www.noah-health.org/english/illness/genetic_diseases/geneticdis.html

http://www.nature.com/cgi-taf/DynaPage.taf?file=/nature/journal/v409/n6822/full/409834a0_fs.html&content_filetype=PDF


(a) What gene or genes is this disorder associated with? What protein does this gene or genes code for? What tissues/organs are affected?

(b) Where is this gene or genes located? How was this gene or group of genes located?

(c) Consider the issue of genetic determinism. Does your gene guarantee the development of the disorder or does it merely predispose an individual toward this disorder in combination with other environmental conditions?

(d) What is the protein?s normal function? Is it, for example, a receptor? An enzyme? A structural protein that makes up some component of the cell?

(e) In individuals with this disorder, is the gene mutated? Is it missing? Is it easily mutated? What is the penetrance of the gene? If you have the mutated gene, what is the chance you will get the disease?

(f) What is this disorder?s mode of inheritance (autosomal or X-linked, dominant or recessive)?

(g) What is the frequency of this mutation? Which populations are at high risk?

(h) Are any treatments available or in development based on this disorder?s genetic underpinnings? How were these treatments developed and/or how do they work? Are there likely side effects? What obstacles block the development of such new treatments? Is gene therapy an option? If treatments based directly on the ?disease gene? are not available, are there ways that knowing whether an individual is a carrier can influence treatment?