Gene Therapy Essays and Research Papers

Instructions for Gene Therapy College Essay Examples

Title: Gene therapy

  • Total Pages: 4
  • Words: 1230
  • Bibliography:0
  • Citation Style: APA
  • Document Type: Essay
Essay Instructions: what are the possible problems with gene therapy? Consider the capitalist angle of anything to make a buck. consider the issue of who gets access to genetic modification. Consider our history of natural selection. From a race/class perspective draw parallels between treatment of (movies Brave new world/Gattaca and people today or how people may act in the future...give pros and cons of gene therapy

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REFERENCES

Author not available (2002). GENE THERAPY BENEFIT SAID TO OUTWEIGH RISK. United Press International.

Elias, Paul (2002).AUL ELIAS, AP Biotechnology Writer, Gene therapy making comeback after French success., AP Worldstream.

Han, Victor (1999). VICTOR HAN, FREELANCE WRITER, SHOULD WE WORRY ABOUT SCIENTISTS ALTERING HUMAN GENES?

O. The London Free Press, pp A9.

Schieszer, John (1996). ARE WE READY FOR DESIGNER GENES? St. Louis Post-Dispatch pp 13B.

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Title: genetic pathway of breast cancer and gene therapy

  • Total Pages: 8
  • Words: 2282
  • Sources:5
  • Citation Style: None
  • Document Type: Research Paper
Essay Instructions: Paper is for Genetics.
I have chosen the topic.
Genetic Pathway of breast cancer and gene therapy as it relates to breast cancer.

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BIBLIOGRAPHY

Abaan, O. D and Criss, Wayne E (2002). Gene therapy in human breast cancer. 32

(2002): 283-291 Turkey Journal of Medical Science: Tubitak. Retrieved on April 15,

2010 from http://journals.tubitak.gov.tr/medical/issues/sag-02-32-4-1-0204.pdf

Lowery, A.J., et al. (2009). MicroRNA signatures predict oestrogen receptor,

progesterone receptor and HER2/neu receptor status in breast cancer. 11 (3) Breast

Cancer Research: BioMed Central, Ltd. Retrieved on April 15, 2010 from http://www.medscape.com/viewarticle/707625

Ma, S. And Kosorok, M.R. (2010). Detection of gene pathways with predictive power for breast cancer prognosis. 11:1 BMC Bioinformatics: BioMed Central. Retrieved on April 16, 2010 from http://www.biomedcentral.com/1471-2105/11/1

Ross, J.S. (2008). Multigene predictors in early-stage breast cancer: moving in or moving out? 8 (2): 129-135 Expert Review of Molecular Diagnostics: Expert

Reviews, Ltd. Retrieved on April 16, 2010 from http://www.medscape.com/viewarticle/575861

Stoff-Khalili M., et al. (2006). Gene therapy for carcinoma of the breast. 13 (7): 33-47

Pub Med: PubMedCentral. Retrieved on April 16, 2010 from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1781527

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Title: Cancer Care

  • Total Pages: 6
  • Words: 1903
  • References:10
  • Citation Style: Harvard
  • Document Type: Essay
Essay Instructions: ALL PDF FILES NEEDED HAVE BEEN UPLOADED.

TOPIC - “critically analyse how scientific developments within cancer care impact upon clinical practice”

The medical focus of the interventions/treatment on Lung Cancer and the physical/psychological impact upon the individual and related care issue.

Address lung cancer explaining how gene therapy is helping, and how radiotherapy has developed along with how this impacts on clinical nurse practices.

Areas that might be included in paper: Cell growth Control and Cancer and Molecules, Genes and cancer

This paper should also contain a critical review of relevant literature.

All scientific aspects that are discussed are balanced with pertinent issues from professional practice.

Note:
This paper is to be written from the point of view of a Cancer NURSE specialist.

There are faxes for this order.

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Bibliography

CDC, "Lung Cancer: Statistics," Accessed!4th Dec 2007, available at http://www.cdc.gov/cancer/lung/statistics/

Caldas, C. (1998) "Science, medicine and the future - Molecular assessment of cancer': British Medical Journal: No.316 pp. 1360-1363,

Available online at, http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1113070

3) Nobuaki Ishii and N. de Tribolet, "Are p53 mutations and p53 over expression prognostic factors for astrocytic tumors? Critical reviews in Neurosurgery, vol 8 / no 5, Sept 1998.

Massion, Pierre P, Taflan, Et, al (Nov 2004), "Early Involvement of the Phosphatidylinositol 3-Kinase/Akt Pathway in Lung Cancer Progression," American Journal of Respiratory and Critical care Medicine,

Heike Allgayer, MD, PHd,(2003), "Molecular Staging of Cancer: Concepts of Today, Therapies of Tomorrow," Journal of Surgical Oncology, 82, 217-223

Karen T. Barker and Richard S. Houlston, "Overgrowth syndromes: Is dysfunctional P. 13 Kinase signalling a Unifying mechanism," European Journal of Human Genetics (2003) 11, 665-670. Available online at, http://www.nature.com/ejhg/journal/v11/n9/full/5201026a.html

Richard C. Duke, David M. Ojcius and John Ding-E Young, (Dec 1996) "Cell Suicide in Health and Disease," Scientific American.

Marissa V Powers and Paul Workman, "Targeting of multiple signaling pathways by heat shock protein 90 molecular chaperone inhibitors," Endocrine-Related Cancer 13, S125-135

ACS, "Gene Therapy for Lung Cancer," Accessed Dec 15th 2007, available at http://www.cancer.org/docroot/NWS/content/NWS_1_1x_Gene_Therapy_for_Lung_Cancer.asp

Wake B.L., Taylor, R.S., Sandercock, J. 'Hyperfractionated/accelerated radiotherapy regimens for the treatment of non-small cell lung cancer. A systematic review of clinical and cost-effectiveness'. Birmingham: University of Birmingham, Department of Public Health and Epidemiology, January 2002.

Lester JF, Macbeth FR, Toy E, Coles B. (2006), "Palliative radiotherapy regimens for non-small cell lung cancer." Cochrane Database of Systematic Reviews, Issue 4. Art. No.: CD002143. DOI: 10.1002/14651858.CD002143.pub2.

Connie Henke Yarbro, Margaret Hansen & Michelle Goodman, "Cancer Nursing: Principles and Practices," Jones and Bartlett Publishers, Sixth edition

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Title: genomics

  • Total Pages: 4
  • Words: 1191
  • Works Cited:0
  • Citation Style: MLA
  • Document Type: Research Paper
Essay Instructions: A 4Page Paper focussing on the recent advances in understanding the genetic underpinnings of one of the five following diseases: alcoholism; using Research Material Provided in the Books and Websites (mandatory)

Use of quotations to support or state claims allowed but must be clearly shown. (Answer Questions a-h in your essay).

Books and Webisites(sources)

1. Freeman, Scott. ?Genomes?. Chapter 16,
2. The Gene Masters: How A New Breed of Scientific Entrepreneurs Raced For the Biggest Prize In Biology. New York: Henry Holt (Times Books), 2002. 5-17, 41-57, 82-92, and 154-59

Websites:-

http://www.ncbi.nlm.nih.gov/disease/

http://www.ncbi.nlm.nih.gov/omim

http://www.noah-health.org/english/illness/genetic_diseases/geneticdis.html

http://www.nature.com/cgi-taf/DynaPage.taf?file=/nature/journal/v409/n6822/full/409834a0_fs.html&content_filetype=PDF


(a) What gene or genes is this disorder associated with? What protein does this gene or genes code for? What tissues/organs are affected?

(b) Where is this gene or genes located? How was this gene or group of genes located?

(c) Consider the issue of genetic determinism. Does your gene guarantee the development of the disorder or does it merely predispose an individual toward this disorder in combination with other environmental conditions?

(d) What is the protein?s normal function? Is it, for example, a receptor? An enzyme? A structural protein that makes up some component of the cell?

(e) In individuals with this disorder, is the gene mutated? Is it missing? Is it easily mutated? What is the penetrance of the gene? If you have the mutated gene, what is the chance you will get the disease?

(f) What is this disorder?s mode of inheritance (autosomal or X-linked, dominant or recessive)?

(g) What is the frequency of this mutation? Which populations are at high risk?

(h) Are any treatments available or in development based on this disorder?s genetic underpinnings? How were these treatments developed and/or how do they work? Are there likely side effects? What obstacles block the development of such new treatments? Is gene therapy an option? If treatments based directly on the ?disease gene? are not available, are there ways that knowing whether an individual is a carrier can influence treatment?

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References

National Institute on Alcohol Abuse (NIAAA). "FAQ's on Alcohol Abuse and Alcoholism." May 14, 2002 at http://www.niaaa.nih.gov/faq/faq.htm

National Center for Biotechnology Information (NCBI). "#103780 Alcoholism." August 15, 2003 at http://www.ncbi.nlm.nih.gov/htbin-post/Omim/dispmim?103780

The Nemours Foundation. "The Basics on Genes and Genetic Disorders." May 2002 at http://www.kidshealth.org/teen/your_body/health_basics/genes_genetic_disorders_p3.html

Centre for Genetic Education. "Gene Therapy." May 2002 at http://www.genetics.com.au/Genetics2003/FactSheets/14.asp

Your Genome.org. "What is a genome?" Feb. 28, 2002 at http://www.yourgenome.org/primer/genomes

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