Fashion Ikedaa, Etsuko. (2009, Et Essay

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113475).

Results

A fully functional tooth developed for the mouse as a result of the experiment. The authors proposed the use of such technology as a model for future organ replacement therapies. "The bioengineered tooth, which was erupted and occluded, had the correct tooth structure, hardness of mineralized tissues for mastication, and response to noxious stimulations such as mechanical stress and pain in cooperation with other oral and maxillofacial tissues" (Ikedaa 2009, p. 113475).

Conclusion

The ability to regenerate fully functional adult teeth could yield considerable improvement in the ease and lifestyle quality for individuals who would previously have to have dental implants.
Clinical

The clinical implications for the success of the study extend far beyond that of the field of dentistry. Stem cell therapy has the potential to restore the partial loss of organ function of neural cells in patients with Parkinson's disease and to generate new organs for individuals suffering other chronic illnesses that affect major organ systems.

References

Ikedaa, Etsuko. (2009, et al.). Fully functional bioengineered tooth replacement as an organ replacement therapy. PNAS. 106 (32): 113475-113480. Retrieved November 4, 2010 at http://www.pnas.org/content/early/2009/07/31/0902944106.full.pdf+html.....

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